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Microtubule Depolymerization by Kinase Inhibitors: Unexpected Findings of Dual Inhibitors
Microtubule-targeting agents are widely used as clinical drugs in the treatment of cancer. However, some kinase inhibitors can also disrupt microtubule organization by directly binding to tubulin. These unexpected effects may result in a plethora of harmful events and/or a misinterpretation of the e...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751111/ https://www.ncbi.nlm.nih.gov/pubmed/29168788 http://dx.doi.org/10.3390/ijms18122508 |