Ketamine, a Clinically Used Anesthetic, Inhibits Vascular Smooth Muscle Cell Proliferation via PP2A-Activated PI3K/Akt/ERK Inhibition

Abnormal proliferation of vascular smooth muscle cells (VSMCs) gives rise to major pathological processes involved in the development of cardiovascular diseases. The use of anti-proliferative agents for VSMCs offers potential for the treatment of vascular disorders. Intravenous anesthetics are firml...

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Detalles Bibliográficos
Autores principales: Chang, Yi, Li, Jiun-Yi, Jayakumar, Thanasekaran, Hung, Shou-Huang, Lee, Wei-Cheng, Manubolu, Manjunath, Sheu, Joen-Rong, Hsu, Ming-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751148/
https://www.ncbi.nlm.nih.gov/pubmed/29186909
http://dx.doi.org/10.3390/ijms18122545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751148/
https://www.ncbi.nlm.nih.gov/pubmed/29186909
http://dx.doi.org/10.3390/ijms18122545

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