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Ketamine, a Clinically Used Anesthetic, Inhibits Vascular Smooth Muscle Cell Proliferation via PP2A-Activated PI3K/Akt/ERK Inhibition
Abnormal proliferation of vascular smooth muscle cells (VSMCs) gives rise to major pathological processes involved in the development of cardiovascular diseases. The use of anti-proliferative agents for VSMCs offers potential for the treatment of vascular disorders. Intravenous anesthetics are firml...
Autores principales: | Chang, Yi, Li, Jiun-Yi, Jayakumar, Thanasekaran, Hung, Shou-Huang, Lee, Wei-Cheng, Manubolu, Manjunath, Sheu, Joen-Rong, Hsu, Ming-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751148/ https://www.ncbi.nlm.nih.gov/pubmed/29186909 http://dx.doi.org/10.3390/ijms18122545 |
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