Impaired Osteogenesis of Disease-Specific Induced Pluripotent Stem Cells Derived from a CFC Syndrome Patient

Cardiofaciocutaneous (CFC) syndrome is a rare genetic disorder caused by mutations in the extracellular signal-regulated kinase (ERK) signaling. However, little is known about how aberrant ERK signaling is associated with the defective bone development manifested in most CFC syndrome patients. In th...

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Detalles Bibliográficos
Autores principales: Choi, Jung-Yun, Han, Kyu-Min, Kim, Dongkyu, Lee, Beom-Hee, Yoo, Han-Wook, Choi, Jin-Ho, Han, Yong-Mahn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751194/
https://www.ncbi.nlm.nih.gov/pubmed/29194391
http://dx.doi.org/10.3390/ijms18122591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751194/
https://www.ncbi.nlm.nih.gov/pubmed/29194391
http://dx.doi.org/10.3390/ijms18122591

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