Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-κB Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-α and the Fas Ligand

Quinacrine has been used for therapeutic drugs in some clinical settings. In the present study, we demonstrated that quinacrine decreased the expression of intercellular adhesion molecule-1 (ICAM-1) induced by tumor necrosis factor (TNF)-α and interleukin-1 (IL-1) α in human lung adenocarcinoma A549...

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Detalles Bibliográficos
Autores principales: Harada, Misuzu, Morimoto, Kyoko, Kondo, Tetsuya, Hiramatsu, Reiko, Okina, Yuji, Muko, Ryo, Matsuda, Iyo, Kataoka, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751206/
https://www.ncbi.nlm.nih.gov/pubmed/29207489
http://dx.doi.org/10.3390/ijms18122603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751206/
https://www.ncbi.nlm.nih.gov/pubmed/29207489
http://dx.doi.org/10.3390/ijms18122603

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