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Glycosaminoglycan-Mediated Downstream Signaling of CXCL8 Binding to Endothelial Cells
The recruitment of leukocytes, mediated by endothelium bound chemokine gradients, is a vital process in inflammation. The highly negatively charged, unbranched polysaccharide family of glycosaminoglycans (GAGs), such as heparan sulfate and chondroitin sulfate mediate chemokine immobilization. Specif...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751208/ https://www.ncbi.nlm.nih.gov/pubmed/29207576 http://dx.doi.org/10.3390/ijms18122605 |