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Glycosaminoglycan-Mediated Downstream Signaling of CXCL8 Binding to Endothelial Cells

The recruitment of leukocytes, mediated by endothelium bound chemokine gradients, is a vital process in inflammation. The highly negatively charged, unbranched polysaccharide family of glycosaminoglycans (GAGs), such as heparan sulfate and chondroitin sulfate mediate chemokine immobilization. Specif...

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Detalles Bibliográficos
Autores principales: Derler, Rupert, Gesslbauer, Bernd, Weber, Corinna, Strutzmann, Elisabeth, Miller, Ingrid, Kungl, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751208/
https://www.ncbi.nlm.nih.gov/pubmed/29207576
http://dx.doi.org/10.3390/ijms18122605