Cargando…
Glycosaminoglycan-Mediated Downstream Signaling of CXCL8 Binding to Endothelial Cells
The recruitment of leukocytes, mediated by endothelium bound chemokine gradients, is a vital process in inflammation. The highly negatively charged, unbranched polysaccharide family of glycosaminoglycans (GAGs), such as heparan sulfate and chondroitin sulfate mediate chemokine immobilization. Specif...
Autores principales: | Derler, Rupert, Gesslbauer, Bernd, Weber, Corinna, Strutzmann, Elisabeth, Miller, Ingrid, Kungl, Andreas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751208/ https://www.ncbi.nlm.nih.gov/pubmed/29207576 http://dx.doi.org/10.3390/ijms18122605 |
Ejemplares similares
-
Targeting of CCL2-CCR2-Glycosaminoglycan Axis Using a CCL2 Decoy Protein Attenuates Metastasis through Inhibition of Tumor Cell Seeding()
por: Roblek, Marko, et al.
Publicado: (2016) -
Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions
por: Joseph, Prem Raj B., et al.
Publicado: (2015) -
CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signaling
por: Giblin, Sean P., et al.
Publicado: (2023) -
CXCL9-Derived Peptides Differentially Inhibit Neutrophil Migration In Vivo through Interference with Glycosaminoglycan Interactions
por: Vanheule, Vincent, et al.
Publicado: (2017) -
Isolation and Characterization of Heparan Sulfate from Human Lung Tissues †
por: Derler, Rupert, et al.
Publicado: (2021)