Duloxetine Protects against Oxaliplatin-Induced Neuropathic Pain and Spinal Neuron Hyperexcitability in Rodents

Oxaliplatin is a widely used chemotherapy agent, but induces serious peripheral neuropathy. Duloxetine is a dual reuptake inhibitor of serotonin and norepinephrine, and is shown to be effective against pain. However, whether and how duloxetine can attenuate oxaliplatin-induced allodynia in rodents i...

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Detalles Bibliográficos
Autores principales: Kim, Woojin, Chung, Yeongu, Choi, Seunghwan, Min, Byung-Il, Kim, Sun Kwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751229/
https://www.ncbi.nlm.nih.gov/pubmed/29206213
http://dx.doi.org/10.3390/ijms18122626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751229/
https://www.ncbi.nlm.nih.gov/pubmed/29206213
http://dx.doi.org/10.3390/ijms18122626

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