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Frequency-Dependent Multi-Well Cardiotoxicity Screening Enabled by Optogenetic Stimulation
Side effects on cardiac ion channels causing lethal arrhythmias are one major reason for drug withdrawals from the market. Field potential (FP) recording from cardiomyocytes, is a well-suited tool to assess such cardiotoxic effects of drug candidates in preclinical drug development, but it is curren...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751237/ https://www.ncbi.nlm.nih.gov/pubmed/29211031 http://dx.doi.org/10.3390/ijms18122634 |