Dihydrocoumarin, an HDAC Inhibitor, Increases DNA Damage Sensitivity by Inhibiting Rad52

Effective DNA repair enables cancer cells to survive DNA damage induced by chemotherapeutic or radiotherapeutic treatments. Therefore, inhibiting DNA repair pathways is a promising therapeutic strategy for increasing the efficacy of such treatments. In this study, we found that dihydrocoumarin (DHC)...

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Detalles Bibliográficos
Autores principales: Chen, Chin-Chuan, Huang, Ju-Sui, Wang, Tong-Hong, Kuo, Chen-Hsin, Wang, Chia-Jen, Wang, Shu-Huei, Leu, Yann-Lii
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751257/
https://www.ncbi.nlm.nih.gov/pubmed/29215575
http://dx.doi.org/10.3390/ijms18122655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751257/
https://www.ncbi.nlm.nih.gov/pubmed/29215575
http://dx.doi.org/10.3390/ijms18122655

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