Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer

Malignant human anaplastic thyroid cancer (ATC) is pertinacious to conventional therapies. The present study investigated the anti-cancer activity of simvastatin and its underlying regulatory mechanism in cultured ATC cells. Simvastatin (0–20 μM) concentration-dependently reduced cell viability and...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Mei-Chieh, Tsai, Yuan-Chin, Tseng, Jen-Ho, Liou, Jr-Jiun, Horng, Steve, Wen, Heng-Ching, Fan, Yu-Ching, Zhong, Wen-Bin, Hsu, Sung-Po
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751292/
https://www.ncbi.nlm.nih.gov/pubmed/29236027
http://dx.doi.org/10.3390/ijms18122690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751292/
https://www.ncbi.nlm.nih.gov/pubmed/29236027
http://dx.doi.org/10.3390/ijms18122690

Ejemplares similares