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Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer
Malignant human anaplastic thyroid cancer (ATC) is pertinacious to conventional therapies. The present study investigated the anti-cancer activity of simvastatin and its underlying regulatory mechanism in cultured ATC cells. Simvastatin (0–20 μM) concentration-dependently reduced cell viability and...
Autores principales: | Chen, Mei-Chieh, Tsai, Yuan-Chin, Tseng, Jen-Ho, Liou, Jr-Jiun, Horng, Steve, Wen, Heng-Ching, Fan, Yu-Ching, Zhong, Wen-Bin, Hsu, Sung-Po |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751292/ https://www.ncbi.nlm.nih.gov/pubmed/29236027 http://dx.doi.org/10.3390/ijms18122690 |
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