Fibrinogen as a Pleiotropic Protein Causing Human Diseases: The Mutational Burden of Aα, Bβ, and γ Chains

Fibrinogen is a highly pleiotropic protein that is involved in the final step of the coagulation cascade, wound healing, inflammation, and angiogenesis. Heterozygous mutations in Aα, Bβ, or γ fibrinogen-chain genes (FGA, FGB, FGG) have been described as being responsible for fibrinogen deficiencies...

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Detalles Bibliográficos
Autores principales: Paraboschi, Elvezia Maria, Duga, Stefano, Asselta, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751312/
https://www.ncbi.nlm.nih.gov/pubmed/29240685
http://dx.doi.org/10.3390/ijms18122711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751312/
https://www.ncbi.nlm.nih.gov/pubmed/29240685
http://dx.doi.org/10.3390/ijms18122711

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