Loss of miR-107, miR-181c and miR-29a-3p Promote Activation of Notch2 Signaling in Pediatric High-Grade Gliomas (pHGGs)

The mechanisms by which microRNAs control pediatric high-grade gliomas (pHGGs) have yet to be fully elucidated. Our studies of patient-derived pHGG tissues and of the pHGG cell line KNS42 revealed down-regulation in these tumors of three microRNAs, specifically miR-107, miR-181c, and miR-29a-3p. Thi...

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Detalles Bibliográficos
Autores principales: Catanzaro, Giuseppina, Sabato, Claudia, Russo, Michele, Rosa, Alessandro, Abballe, Luana, Besharat, Zein Mersini, Po, Agnese, Miele, Evelina, Bellavia, Diana, Chiacchiarini, Martina, Gessi, Marco, Peruzzi, Giovanna, Napolitano, Maddalena, Antonelli, Manila, Mastronuzzi, Angela, Giangaspero, Felice, Locatelli, Franco, Screpanti, Isabella, Vacca, Alessandra, Ferretti, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751342/
https://www.ncbi.nlm.nih.gov/pubmed/29258209
http://dx.doi.org/10.3390/ijms18122742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751342/
https://www.ncbi.nlm.nih.gov/pubmed/29258209
http://dx.doi.org/10.3390/ijms18122742

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