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Sulfuretin Attenuates MPP(+)-Induced Neurotoxicity through Akt/GSK3β and ERK Signaling Pathways

Parkinson’s disease (PD) is the second most common neurodegenerative disease. It is caused by the death of dopaminergic neurons in the substantia nigra pars compacta. Oxidative stress and mitochondrial dysfunction contribute to the loss of dopaminergic neurons in PD. Sulfuretin is a potent antioxida...

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Detalles Bibliográficos
Autores principales: Pariyar, Ramesh, Lamichhane, Ramakanta, Jung, Hyun Ju, Kim, Sung Yeon, Seo, Jungwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751352/
https://www.ncbi.nlm.nih.gov/pubmed/29257079
http://dx.doi.org/10.3390/ijms18122753