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Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4(+) T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis

Microsomal prostaglandin synthetase-1 (mPGES-1) is an inducible terminal enzyme that produces prostaglandin E(2) (PGE(2)). In our previous study, we investigated the role of mPGES-1 in the inflammation and demyelination observed in experimental autoimmune encephalomyelitis (EAE), an animal model of...

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Detalles Bibliográficos
Autores principales: Takemiya, Takako, Takeuchi, Chisen, Kawakami, Marumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751357/
https://www.ncbi.nlm.nih.gov/pubmed/29257087
http://dx.doi.org/10.3390/ijms18122758