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Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4(+) T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis
Microsomal prostaglandin synthetase-1 (mPGES-1) is an inducible terminal enzyme that produces prostaglandin E(2) (PGE(2)). In our previous study, we investigated the role of mPGES-1 in the inflammation and demyelination observed in experimental autoimmune encephalomyelitis (EAE), an animal model of...
Autores principales: | Takemiya, Takako, Takeuchi, Chisen, Kawakami, Marumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751357/ https://www.ncbi.nlm.nih.gov/pubmed/29257087 http://dx.doi.org/10.3390/ijms18122758 |
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