Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation

Alzheimer’s disease (AD) is characterized by extracellular plaques in the brain, mainly consisting of amyloid-β (Aβ), as derived from sequential cleavage of the amyloid precursor protein. Epidemiological studies suggest a tight link between hypovitaminosis of the secosteroid vitamin D and AD. Beside...

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Detalles Bibliográficos
Autores principales: Grimm, Marcus O. W., Thiel, Andrea, Lauer, Anna A., Winkler, Jakob, Lehmann, Johannes, Regner, Liesa, Nelke, Christopher, Janitschke, Daniel, Benoist, Céline, Streidenberger, Olga, Stötzel, Hannah, Endres, Kristina, Herr, Christian, Beisswenger, Christoph, Grimm, Heike S., Bals, Robert, Lammert, Frank, Hartmann, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751363/
https://www.ncbi.nlm.nih.gov/pubmed/29257109
http://dx.doi.org/10.3390/ijms18122764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751363/
https://www.ncbi.nlm.nih.gov/pubmed/29257109
http://dx.doi.org/10.3390/ijms18122764

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