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Lipopolysaccharide-Induced Acute Kidney Injury Is Dependent on an IL-18 Receptor Signaling Pathway

The proinflammatory cytokine interleukin (IL)-18 is an important mediator of the organ failure induced by endotoxemia. IL-18 (known as an interferon-gamma (IFN-γ) inducing factor), and other inflammatory cytokines have important roles in lipopolysaccharide (LPS)-induced acute kidney injury (AKI). We...

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Detalles Bibliográficos
Autores principales: Nozaki, Yuji, Hino, Shoichi, Ri, Jinhai, Sakai, Kenji, Nagare, Yasuaki, Kawanishi, Mai, Niki, Kaoru, Funauchi, Masanori, Matsumura, Itaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751375/
https://www.ncbi.nlm.nih.gov/pubmed/29261164
http://dx.doi.org/10.3390/ijms18122777