Utilizing random Forest QSAR models with optimized parameters for target identification and its application to target-fishing server

BACKGROUND: The identification of target molecules is important for understanding the mechanism of “target deconvolution” in phenotypic screening and “polypharmacology” of drugs. Because conventional methods of identifying targets require time and cost, in-silico target identification has been consi...

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Detalles Bibliográficos
Autores principales: Lee, Kyoungyeul, Lee, Minho, Kim, Dongsup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751401/
https://www.ncbi.nlm.nih.gov/pubmed/29297315
http://dx.doi.org/10.1186/s12859-017-1960-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751401/
https://www.ncbi.nlm.nih.gov/pubmed/29297315
http://dx.doi.org/10.1186/s12859-017-1960-x

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