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Automated classification and characterization of the mitotic spindle following knockdown of a mitosis-related protein

BACKGROUND: Cell division (mitosis) results in the equal segregation of chromosomes between two daughter cells. The mitotic spindle plays a pivotal role in chromosome alignment and segregation during metaphase and anaphase. Structural or functional errors of this spindle can cause aneuploidy, a hall...

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Detalles Bibliográficos
Autores principales: Khushi, Matloob, Dean, Imraan M., Teber, Erdahl T., Chircop, Megan, Arthur, Jonathan W., Flores-Rodriguez, Neftali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751558/
https://www.ncbi.nlm.nih.gov/pubmed/29297284
http://dx.doi.org/10.1186/s12859-017-1966-4