Repositioning drugs by targeting network modules: a Parkinson’s disease case study

BACKGROUND: Much effort has been devoted to the discovery of specific mechanisms between drugs and single targets to date. However, as biological systems maintain homeostasis at the level of functional networks robustly controlling the internal environment, such networks commonly contain multiple re...

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Detalles Bibliográficos
Autores principales: Yue, Zongliang, Arora, Itika, Zhang, Eric Y., Laufer, Vincent, Bridges, S. Louis, Chen, Jake Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751600/
https://www.ncbi.nlm.nih.gov/pubmed/29297292
http://dx.doi.org/10.1186/s12859-017-1889-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751600/
https://www.ncbi.nlm.nih.gov/pubmed/29297292
http://dx.doi.org/10.1186/s12859-017-1889-0

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