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Repositioning drugs by targeting network modules: a Parkinson’s disease case study
BACKGROUND: Much effort has been devoted to the discovery of specific mechanisms between drugs and single targets to date. However, as biological systems maintain homeostasis at the level of functional networks robustly controlling the internal environment, such networks commonly contain multiple re...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751600/ https://www.ncbi.nlm.nih.gov/pubmed/29297292 http://dx.doi.org/10.1186/s12859-017-1889-0 |