CORNAS: coverage-dependent RNA-Seq analysis of gene expression data without biological replicates

BACKGROUND: In current statistical methods for calling differentially expressed genes in RNA-Seq experiments, the assumption is that an adjusted observed gene count represents an unknown true gene count. This adjustment usually consists of a normalization step to account for heterogeneous sample lib...

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Detalles Bibliográficos
Autores principales: Low, Joel Z. B., Khang, Tsung Fei, Tammi, Martti T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751784/
https://www.ncbi.nlm.nih.gov/pubmed/29297307
http://dx.doi.org/10.1186/s12859-017-1974-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751784/
https://www.ncbi.nlm.nih.gov/pubmed/29297307
http://dx.doi.org/10.1186/s12859-017-1974-4

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