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CORNAS: coverage-dependent RNA-Seq analysis of gene expression data without biological replicates

BACKGROUND: In current statistical methods for calling differentially expressed genes in RNA-Seq experiments, the assumption is that an adjusted observed gene count represents an unknown true gene count. This adjustment usually consists of a normalization step to account for heterogeneous sample lib...

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Detalles Bibliográficos
Autores principales:	Low, Joel Z. B., Khang, Tsung Fei, Tammi, Martti T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751784/ https://www.ncbi.nlm.nih.gov/pubmed/29297307 http://dx.doi.org/10.1186/s12859-017-1974-4

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