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Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations

BACKGROUND: Invasive cribriform and intraductal carcinoma (CR/IDC) is associated with adverse outcome of prostate cancer patients. The aim of this study was to determine the molecular aberrations associated with CR/IDC in primary prostate cancer, focusing on genomic instability and somatic copy numb...

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Detalles Bibliográficos
Autores principales: Böttcher, René, Kweldam, Charlotte F., Livingstone, Julie, Lalonde, Emilie, Yamaguchi, Takafumi N., Huang, Vincent, Yousif, Fouad, Fraser, Michael, Bristow, Robert G., van der Kwast, Theodorus, Boutros, Paul C., Jenster, Guido, van Leenders, Geert J. L. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751811/
https://www.ncbi.nlm.nih.gov/pubmed/29295717
http://dx.doi.org/10.1186/s12885-017-3976-z