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Upregulation of Mas-related G Protein coupled receptor X2 in asthmatic lung mast cells and its activation by the novel neuropeptide hemokinin-1

Hemokinin-1 (HK-1) is a novel neuropeptide produced by human bronchial cells and macrophages and causes contraction of human bronchi ex vivo. It is also generated by antigen/IgE-activated murine mast cells (MCs) and contributes to experimental chronic allergic airway inflammation via the activation...

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Detalles Bibliográficos
Autores principales: Manorak, Wichayapha, Idahosa, Chizobam, Gupta, Kshitij, Roy, Saptarshi, Panettieri, Reynold, Ali, Hydar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751818/
https://www.ncbi.nlm.nih.gov/pubmed/29295703
http://dx.doi.org/10.1186/s12931-017-0698-3