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Statistical methods to compare functional outcomes in randomized controlled trials with high mortality

Mortality is a common primary endpoint in randomized controlled trials of patients with a high severity of illness, such as critically ill patients. However, researchers are increasingly evaluating functional outcomes, such as quality of life. Importantly, in such trials some patients may die before...

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Detalles Bibliográficos
Autores principales: Colantuoni, Elizabeth, Scharfstein, Daniel O, Wang, Chenguang, Hashem, Mohamed D, Leroux, Andrew, Needham, Dale M, Girard, Timothy D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751848/
https://www.ncbi.nlm.nih.gov/pubmed/29298779
http://dx.doi.org/10.1136/bmj.j5748