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Orally administered endoxifen inhibits tumor growth in melanoma-bearing mice

Endoxifen, an active metabolite of tamoxifen, has been shown to be an effective anti-estrogenic agent in estrogen receptor-positive breast cancer patients. In melanoma, estrogen receptor expression is shown to be associated with disease progression. However, the therapeutic benefit of endoxifen in m...

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Detalles Bibliográficos
Autores principales: Chen, Paul, Sheikh, Saifuddin, Ahmad, Ateeq, Ali, Shoukath M., Ahmad, Moghis U., Ahmad, Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751858/
https://www.ncbi.nlm.nih.gov/pubmed/29308069
http://dx.doi.org/10.1186/s11658-017-0068-7