Characterization of a candidate tetravalent vaccine based on 2'-O-methyltransferase mutants

Dengue virus (DENV) is one of the most widespread arboviruses. The four DENV serotypes infect about 400 million people every year, causing 96 million clinical dengue cases, of which approximately 500’000 are severe and potentially life-threatening. The only licensed vaccine has a limited efficacy an...

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Detalles Bibliográficos
Autores principales: Züst, Roland, Li, Shi-Hua, Xie, Xuping, Velumani, Sumathy, Chng, Melissa, Toh, Ying-Xiu, Zou, Jing, Dong, Hongping, Shan, Chao, Pang, Jassia, Qin, Cheng-Feng, Newell, Evan W., Shi, Pei-Yong, Fink, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751980/
https://www.ncbi.nlm.nih.gov/pubmed/29298302
http://dx.doi.org/10.1371/journal.pone.0189262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751980/
https://www.ncbi.nlm.nih.gov/pubmed/29298302
http://dx.doi.org/10.1371/journal.pone.0189262

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