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Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance

Despite significant advances in cancer treatment and management, more than 60% of patients with neuroblastoma present with very poor prognosis in the form of metastatic and aggressive disease. Solid tumors including neuroblastoma are thought to be heterogeneous with a sub-population of stem-like cel...

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Detalles Bibliográficos
Autores principales: Abou-Antoun, Tamara J., Nazarian, Javad, Ghanem, Anthony, Vukmanovic, Stanislav, Sandler, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751995/
https://www.ncbi.nlm.nih.gov/pubmed/29298329
http://dx.doi.org/10.1371/journal.pone.0189711