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Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance
Despite significant advances in cancer treatment and management, more than 60% of patients with neuroblastoma present with very poor prognosis in the form of metastatic and aggressive disease. Solid tumors including neuroblastoma are thought to be heterogeneous with a sub-population of stem-like cel...
Autores principales: | Abou-Antoun, Tamara J., Nazarian, Javad, Ghanem, Anthony, Vukmanovic, Stanislav, Sandler, Anthony D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751995/ https://www.ncbi.nlm.nih.gov/pubmed/29298329 http://dx.doi.org/10.1371/journal.pone.0189711 |
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