Pentosan polysulfate ameliorates apoptosis and inflammation by suppressing activation of the p38 MAPK pathway in high glucose-treated HK-2 cells

The apoptosis of tubular epithelial cells in diabetic nephropathy (DN) is commonly observed in human renal biopsies. Inflammation plays a key role in DN, and pentosan polysulfate (PPS) has been shown to largely attenuate the inflammation of nephropathy in aging diabetic mice. p38 mitogen-activated p...

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Detalles Bibliográficos
Autores principales: Chen, Ping, Yuan, Yang, Zhang, Tianying, Xu, Bo, Gao, Qing, Guan, Tianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752165/
https://www.ncbi.nlm.nih.gov/pubmed/29207166
http://dx.doi.org/10.3892/ijmm.2017.3290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752165/
https://www.ncbi.nlm.nih.gov/pubmed/29207166
http://dx.doi.org/10.3892/ijmm.2017.3290

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