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Effects of kartogenin on the attenuated nucleus pulposus cell degeneration of intervertebral discs induced by interleukin-1β and tumor necrosis factor-α

Cytokines are the main cause of intervertebral disc degeneration. Kartogenin (KGN) is found to protect chondrocytes from cytokines. To explore whether KGN can slow down the degeneration on intervertebral discs following exposure to interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α), the expr...

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Detalles Bibliográficos
Autores principales: Huang, Yao, Jiang, Tao, Chen, Jian, Yin, Guo-Yong, Fan, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752177/
https://www.ncbi.nlm.nih.gov/pubmed/29207013
http://dx.doi.org/10.3892/ijmm.2017.3283