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Effects of kartogenin on the attenuated nucleus pulposus cell degeneration of intervertebral discs induced by interleukin-1β and tumor necrosis factor-α
Cytokines are the main cause of intervertebral disc degeneration. Kartogenin (KGN) is found to protect chondrocytes from cytokines. To explore whether KGN can slow down the degeneration on intervertebral discs following exposure to interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α), the expr...
Autores principales: | Huang, Yao, Jiang, Tao, Chen, Jian, Yin, Guo-Yong, Fan, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752177/ https://www.ncbi.nlm.nih.gov/pubmed/29207013 http://dx.doi.org/10.3892/ijmm.2017.3283 |
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