Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases

TOR complex 1 (TORC1) is an evolutionarily conserved protein kinase complex that promotes cellular macromolecular synthesis and suppresses autophagy. Amino-acid-induced activation of mammalian TORC1 is initiated by its recruitment to the RagA/B-RagC/D GTPase heterodimer, which is anchored to lysosom...

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Detalles Bibliográficos
Autores principales: Chia, Kim Hou, Fukuda, Tomoyuki, Sofyantoro, Fajar, Matsuda, Takato, Amai, Takamitsu, Shiozaki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752196/
https://www.ncbi.nlm.nih.gov/pubmed/29199950
http://dx.doi.org/10.7554/eLife.30880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752196/
https://www.ncbi.nlm.nih.gov/pubmed/29199950
http://dx.doi.org/10.7554/eLife.30880

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