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Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length

Muscle fiber length is nearly uniform within a muscle but widely different among different muscles. We show that Abelson tyrosine-protein kinase 2 (Abl2) has a key role in regulating myofiber length, as a loss of Abl2 leads to excessively long myofibers in the diaphragm, intercostal and levator auri...

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Detalles Bibliográficos
Autores principales: Lee, Jennifer K, Hallock, Peter T, Burden, Steven J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752197/
https://www.ncbi.nlm.nih.gov/pubmed/29231808
http://dx.doi.org/10.7554/eLife.29905