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A common African variant of human connexin 37 is associated with Caucasian primary ovarian insufficiency and has a deleterious effect in vitro

Folliculogenesis requires communication between granulosa cells and oocytes, mediated by connexin-based gap junctions. Connexin 37 (Cx37)-deficient female mice are infertile. The present study assessed Cx37 deficiency in patients with primary ovarian insufficiency (POI). A candidate gene study was p...

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Detalles Bibliográficos
Autores principales: Bachelot, Anne, Gilleron, Jerome, Meduri, Geri, Guberto, Mihelai, Dulon, Jerome, Boucherie, Sylviane, Touraine, Philippe, Misrahi, Micheline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752242/
https://www.ncbi.nlm.nih.gov/pubmed/29207017
http://dx.doi.org/10.3892/ijmm.2017.3257