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Small interfering RNA-mediated silencing of G-protein-coupled receptor 137 inhibits growth of osteosarcoma cells

PURPOSE: Osteosarcoma is the most widespread primary carcinoma in bones. Osteosarcoma cells are highly metastatic and frequently develop resistance to chemotherapy making this disease harder to treat. This identifies an urgent need of novel therapeutic strategies for osteosarcoma. G-Protein-coupled...

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Detalles Bibliográficos
Autores principales: Li, Hao, Fu, Xiaodong, Gao, Yingjian, Li, Xiaomiao, Shen, Yi, Wang, Weili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752330/
https://www.ncbi.nlm.nih.gov/pubmed/29321966
http://dx.doi.org/10.1016/j.jbo.2017.12.001