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In Vivo SELEX of an Inhibitory NSCLC-Specific RNA Aptamer from PEGylated RNA Library

Aptamers are widely used in numerous biochemical, bioanalytical, and biological studies. Most aptamers are developed through an in vitro selection process called SELEX against either purified targets or living cells expressing targets of interest. We report here an in vivo SELEX in mice using a PEGy...

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Detalles Bibliográficos
Autores principales: Wang, Hanlu, Zhang, Yibang, Yang, Haiping, Qin, Meng, Ding, Xinxin, Liu, Rihe, Jiang, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752333/
https://www.ncbi.nlm.nih.gov/pubmed/29499932
http://dx.doi.org/10.1016/j.omtn.2017.12.003