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Regulatory T cells with a defect in inhibition on co-stimulation deteriorated primary biliary cholangitis

Regulatory T cells (Tregs) play an indispensable role in the progression of primary biliary cholangitis (PBC). Although Tregs could normalize costimulation in in vivo and in vitro models, it is obscure whether and how Tregs mediate these effects in PBC. Herein we focused on the quantitative and func...

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Detalles Bibliográficos
Autores principales: Chen, Jianing, Hou, Xianliang, Jia, Hongyu, Cui, Guangying, Wu, Zhongwen, Wang, Lin, Lu, Chong, Wu, Wei, Wei, Yingfeng, Uede, Toshimitsu, Li, Lanjuan, Lian, Zhexiong, Diao, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752452/
https://www.ncbi.nlm.nih.gov/pubmed/29312539
http://dx.doi.org/10.18632/oncotarget.22658