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Tripterygium Wilfordii inhibits tonsillar IgA production by downregulating IgA class switching in IgA nephropathy

IgA nephropathy (IgAN) is characterized by high serum IgA levels and IgA deposition in the renal mesangium. Recent research has indicated that pathogenic IgA may originate from affected tonsils, where present enhancement of IgA production by IgA class switching and immuno-activation. Tripterygium Wi...

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Detalles Bibliográficos
Autores principales: Li, Huining, Kong, Dan, Xu, Yangyang, Li, Xiaomei, Yao, Guodong, Chen, Kexin, You, Qi, Shi, Qingtao, Zhang, Lei, Wang, Xin, Yuan, Dawei, Miao, Shusheng, Geng, Jingshu, Jin, Xiaoming, Meng, Hongxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752501/
https://www.ncbi.nlm.nih.gov/pubmed/29312588
http://dx.doi.org/10.18632/oncotarget.22561