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RA and ω-3 PUFA co-treatment activates autophagy in cancer cells

Retinoic acid (RA), is a promising therapeutic agent for the treatment of breast cancer. However, metabolic disorders and drug resistance reduce the efficacy of RA. In this study, we found that RA and ω-3 polyunsaturated fatty acids (ω-3 PUFAs) synergistically induced cell death in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Zhu, Shenglong, Lin, Guangxiao, Song, Ci, Wu, Yikuan, Feng, Ninghan, Chen, Wei, He, Zhao, Chen, Yong Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752509/
https://www.ncbi.nlm.nih.gov/pubmed/29312596
http://dx.doi.org/10.18632/oncotarget.22629