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Mild hypothermia modulates the expression of nestin and caspase-3 in the sub-granular zone and improves neurological outcomes in rats with ischemic stroke

We assessed neurological outcomes, infarct volume, and the expression of nestin and caspase-3 in the hippocampal dentate gyrus following middle cerebral artery occlusion (MCAO) followed by reperfusion, with mild hypothermia (MH) treatment at the onset of ischemia in a MCAO rat model. Reperfusion beg...

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Detalles Bibliográficos
Autores principales: Yu, Dan, Wang, Xueying, Zhou, Feng, Wang, Liang, Yang, Guoshuai, Zhong, Wei, Li, Ying, Zhou, Zhiping, Wang, Aiyue, Zhou, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752513/
https://www.ncbi.nlm.nih.gov/pubmed/29312600
http://dx.doi.org/10.18632/oncotarget.22647