Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis

Hepatocellular carcinoma (HCC) is one of the most frequent cancers. In vitro studies suggest that growth and response to therapy of human carcinomas may depend on glycosphingolipid (GSL) expression. Glucosylceramide synthase (GCS), encoded by the gene Ugcg, is the basic enzyme required for the synth...

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Detalles Bibliográficos
Autores principales: Jennemann, Richard, Federico, Giuseppina, Mathow, Daniel, Rabionet, Mariona, Rampoldi, Francesca, Popovic, Zoran V., Volz, Martina, Hielscher, Thomas, Sandhoff, Roger, Gröne, Hermann-Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752514/
https://www.ncbi.nlm.nih.gov/pubmed/29312601
http://dx.doi.org/10.18632/oncotarget.22648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752514/
https://www.ncbi.nlm.nih.gov/pubmed/29312601
http://dx.doi.org/10.18632/oncotarget.22648

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