Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression

Although interaction between BMP and Notch signaling has been demonstrated to be crucial for osteogenic differentiation of mesenchymal stem cells (MSCs), the precise molecular mechanism remains unknown. Here, we show that Notch intracellular domain (NICD) overexpression inhibits BMP9-induced C3H10T1...

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Detalles Bibliográficos
Autores principales: Wang, Nan, Liu, Wei, Tan, Tao, Dong, Chao-Qun, Lin, Duan-Yang, Zhao, Jun, Yu, Chang, Luo, Xiao-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752550/
https://www.ncbi.nlm.nih.gov/pubmed/29312637
http://dx.doi.org/10.18632/oncotarget.22763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752550/
https://www.ncbi.nlm.nih.gov/pubmed/29312637
http://dx.doi.org/10.18632/oncotarget.22763

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