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Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression
Although interaction between BMP and Notch signaling has been demonstrated to be crucial for osteogenic differentiation of mesenchymal stem cells (MSCs), the precise molecular mechanism remains unknown. Here, we show that Notch intracellular domain (NICD) overexpression inhibits BMP9-induced C3H10T1...
Autores principales: | Wang, Nan, Liu, Wei, Tan, Tao, Dong, Chao-Qun, Lin, Duan-Yang, Zhao, Jun, Yu, Chang, Luo, Xiao-Ji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752550/ https://www.ncbi.nlm.nih.gov/pubmed/29312637 http://dx.doi.org/10.18632/oncotarget.22763 |
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