Progranulin derived engineered protein Atsttrin suppresses TNF-α-mediated inflammation in intervertebral disc degenerative disease

Atsttrin, an engineered molecule composed of three fragments of progranulin(PGRN), exerts comparable anti-inflammation ability. Intervertebral disc degeneration (IDD) is involved in inflammation in which TNF-α plays a key role. This study aims to examine the effect and the mechanism of Atsttrin in t...

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Detalles Bibliográficos
Autores principales: Ding, Hong, Wei, Jianlu, Zhao, Yunpeng, Liu, Yi, Liu, Lian, Cheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752552/
https://www.ncbi.nlm.nih.gov/pubmed/29312639
http://dx.doi.org/10.18632/oncotarget.22766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752552/
https://www.ncbi.nlm.nih.gov/pubmed/29312639
http://dx.doi.org/10.18632/oncotarget.22766

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