Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors

Membrane dynamic processes including vesicle biogenesis depend on Arf GTPase activation by guanine nucleotide exchange factors (GEFs) containing a catalytic Sec7 domain and a membrane targeting module such as a PH domain. The catalytic output of cytohesin family Arf GEFs is controlled by autoinhibit...

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Detalles Bibliográficos
Autores principales: Malaby, Andrew W., Das, Sanchaita, Chakravarthy, Srinivas, Irving, Thomas C., Bilsel, Osman, Lambright, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752578/
https://www.ncbi.nlm.nih.gov/pubmed/29276036
http://dx.doi.org/10.1016/j.str.2017.11.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752578/
https://www.ncbi.nlm.nih.gov/pubmed/29276036
http://dx.doi.org/10.1016/j.str.2017.11.019

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