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Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors
Membrane dynamic processes including vesicle biogenesis depend on Arf GTPase activation by guanine nucleotide exchange factors (GEFs) containing a catalytic Sec7 domain and a membrane targeting module such as a PH domain. The catalytic output of cytohesin family Arf GEFs is controlled by autoinhibit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752578/ https://www.ncbi.nlm.nih.gov/pubmed/29276036 http://dx.doi.org/10.1016/j.str.2017.11.019 |